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Article

N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux.

Neuroscience - 14 Feb 2014

Torres B, Ruoho A E

Abstract excerpt

The 20 amino acid (AA) N-terminus of the vesicular monoamine transporter 2 (VMAT2) was examined as a regulator of VMAT2 function. Removal of the first 16 or 19 AAs of the N-terminus resulted in a molecule with reduced ability to sequester [(3)H]-5HT. A glutathione-S-transferase-construct of the N-terminus underwent phosphorylation in the presence of PKC at serines 15 and 18. These putative phosphorylation sites...

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Identifiers

PMID: 24321511
DOI: 10.1016/j.neuroscience.2013.11.059
PMCID: PMC3926813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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