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Article

Transcription factor Ets1, but not the closely related factor Ets2, inhibits antibody-secreting cell differentiation.

Molecular and cellular biology - 1 Feb 2014

John Shinu, Russell Lisa, Chin Shu Shien, Luo Wei, Oshima Robert, Garrett-Sinha Lee Ann

Abstract excerpt

B cell differentiation into antibody-secreting cells (ASCs) is a tightly regulated process under the control of multiple transcription factors. One such transcription factor, Ets1, blocks the transition of B cells to ASCs via two separate activities: (i) stimulating the expression of target genes that promote B cell identity and (ii) interfering with the functional activity of the transcription factor Blimp1....

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Identifiers

PMID: 24277931
DOI: 10.1128/MCB.00612-13
PMCID: PMC3911503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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