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Article

Characterization of ABF-1, a Novel Basic Helix-Loop-Helix Transcription Factor Expressed in Activated B Lymphocytes

1 Jun 1998

Abstract excerpt

Proteins of the basic helix-loop-helix (bHLH) family are required for a number of different developmental pathways, including neurogenesis, lymphopoiesis, myogenesis, and sex determination. Using a yeast two-hybrid screen, we have identified a new bHLH transcription factor, ABF-1, from a human B-cell cDNA library. Within the bHLH region, ABF-1 shows a remarkable conservation with other HLH proteins, including...

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Identifiers

PMID: 9584154
DOI: 10.1128/mcb.18.6.3130

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Source receipt: pubmed, retrieved 7 Sept 2026.

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