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Article

Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function.

BMC medical genetics - 25 Nov 2013

Reardon Brian J, Hansen Joyanna G, Crystal Ronald G, Houston Denise K, Kritchevsky Stephen B, Harris Tamara, Lohman Kurt, Liu Yongmei, O'Connor George T, Wilk Jemma B, Mezey Jason, Gao Chuan, Cassano Patricia A

Abstract excerpt

BACKGROUND: Vitamin D is associated with lung health in epidemiologic studies, but mechanisms mediating observed associations are poorly understood. This study explores mechanisms for an effect of vitamin D in lung through an in vivo gene expression study, an expression quantitative trait loci (eQTL) analysis in lung tissue, and a population-based cohort study of sequence variants. METHODS: Microarray analysis...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24274704
DOI: 10.1186/1471-2350-14-122
PMCID: PMC3907038

Genes

SGPP2
DAPK1
FSTL1
KCNS3
RSAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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