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Article

Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function.

American journal of respiratory and critical care medicine - 15 Feb 2012

Qiu Weiliang, Baccarelli Andrea, Carey Vincent J, Boutaoui Nadia, Bacherman Helene, Klanderman Barbara, Rennard Stephen, Agusti Alvar, Anderson Wayne, Lomas David A, DeMeo Dawn L

Abstract excerpt

RATIONALE: Chronic obstructive pulmonary disease (COPD) is associated with local (lung) and systemic (blood) inflammation and manifestations. DNA methylation is an important regulator of gene transcription, and global and specific gene methylation marks may vary with cigarette smoke exposure. OBJECTIVES: To perform a comprehensive assessment of methylation marks in DNA from subjects well phenotyped for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Pulmonary Disease, Chronic Obstructive

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Source

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Identifiers

PMID: 22161163
DOI: 10.1164/rccm.201108-1382OC
PMCID: PMC3297093

Genes

FEV
SERPINA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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