Article

Meta-analysis of exome array data identifies six novel genetic loci for lung function

2018-08-07

Abstract excerpt

<h4>Background: </h4> Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. <h4>Methods: </h4>: We carried out meta-analyses of exome array data and three lung function measures: forced expiratory volume in one second (FEV 1 ), forced vital capacity (FVC) and the ratio of FEV 1 to FVC (FEV 1 /FVC). These...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: af1f4e63-6382-5194-9c7f-d51e3942172d
DOI: 10.12688/wellcomeopenres.12583.3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Meta-analysis of exome array data identifies six novel genetic loci for lung functionDOI 10.12688/wellcomeopenres.12583.3Read

Meta-analysis of exome array data identifies six novel genetic loci for lung functionSemantic proximity Read

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.Semantic proximity Read

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.Semantic proximity Read

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung functionSemantic proximity Read

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets.Semantic proximity Read

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.Semantic proximity Read

Multi-ancestry genome-wide association study improves resolution of genes, pathways and pleiotropy for lung function and chronic obstructive pulmonary diseaseSemantic proximity Read

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestriesSemantic proximity Read

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants.Semantic proximity Read

Whole Genome Sequence Analysis of Pulmonary Function and COPD in 44,287 Multi-ancestry ParticipantsSemantic proximity Read

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.Semantic proximity Read

Genetic susceptibility to COPD: Systematic review, bibliometric analysis and meta-analysis of SERPINA1, HHIP, IREB2, SFTPD, and FAM13A.Semantic proximity Read