Article
Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease.
American journal of respiratory cell and molecular biology - 1 Aug 2015
Hansel Nadia N, Paré Peter D, Rafaels Nicholas, Sin Don D, Sandford Andrew, Daley Denise, Vergara Candelaria, Huang Lili, Elliott W Mark, Pascoe Chris D, Arsenault Bryna A, Postma Dirkje S, Boezen H Marike, Bossé Yohan, van den Berge Maarten, Hiemstra Pieter S, Cho Michael H, Litonjua Augusto A, Sparrow David, Ober Carole, Wise Robert A, Connett John, Neptune Enid R, Beaty Terri H, Ruczinski Ingo, Mathias Rasika A, Barnes Kathleen C
Abstract excerpt
Increased airway responsiveness is linked to lung function decline and mortality in subjects with chronic obstructive pulmonary disease (COPD); however, the genetic contribution to airway responsiveness remains largely unknown. A genome-wide association study (GWAS) was performed using the Illumi...
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