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Epigenome-Wide Association Study of Chronic Obstructive Pulmonary Disease and Lung Function in Koreans

16 Jun 2017

Abstract excerpt

AIM: To identify differentially methylated probes (DMPs) and regions (DMRs) in relation to chronic obstructive pulmonary disease (COPD) and lung function traits. METHODS: We performed an epigenome-wide association study of COPD and spirometric parameters, including forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV1/FVC, in blood DNA using the Infinium HumanMethylation450 (n = 100, a...

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PMID: 28621160
DOI: 10.2217/epi-2017-0002

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