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Article

Simultaneous estimation of gene-gene and gene-environment interactions for numerous loci using double penalized log-likelihood.

Genetic epidemiology - 1 Dec 2006

Tanck Michael W T, Jukema J Wouter, Zwinderman Aeilko H

Abstract excerpt

Many common human diseases are considered to be caused by complex multifactorial processes. For these diseases, it is expected that numerous genetic and environmental factors and, possibly, their interactions play a role. Therefore, simultaneously analyzing the effects of numerous genes and environmental factors is a more realistic approach compared to single gene analyses, but the large number of genes and...

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PMID: 16917921
DOI: 10.1002/gepi.20176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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