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Article

Forward LASSO analysis for high-order interactions in genome-wide association study.

Briefings in bioinformatics - 1 Jul 2014

Gao Huijiang, Wu Yang, Li Jiahan, Li Hongwang, Li Junya, Yang Runqing

Abstract excerpt

Previous genome-wide association study (GWAS) focused on low-order interactions between pairwise single-nucleotide polymorphisms (SNPs) with significant main effects. Little is known how high-order interactions effect, especially one among the SNPs without main effects regulates quantitative traits. Within the frameworks of linear model and generalized linear model, the LASSO with coordinate descent step can be...

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PMID: 23775311
DOI: 10.1093/bib/bbt037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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