Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TLR9 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis.

PloS one - 1 Jan 2013

Wang Xiaoyong, Xue Lening, Yang Yang, Xu Lijuan, Zhang Guoxin

Abstract excerpt

OBJECTIVE: Genetic polymorphisms of Toll-like receptors (TLRs) may influence the effects of H. pylori infection and play important roles in gastric carcinogenesis. The aim of this study was to determine whether the polymorphisms of TLR4 and TLR9 are associated with susceptibility to gastric carcinoma and its prognosis. METHODS: This study consisted of 314 patients with gastric cancer and 314 healthy controls. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Carcinoma
Share to Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Logistic Models

Share to Odds Ratio

Share to Sex Factors

Share to Stomach Neoplasms

Share to Toll-Like Receptor 9

Source

Open in PubMed Open full text

Identifiers

PMID: 23776537
DOI: 10.1371/journal.pone.0065731
PMCID: PMC3680499

Genes

TLR9
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TLR9 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis.PMID 23776537Read ↗

Polymorphisms of TLR9 gene are associated with a decreased risk of H. pylori infection in a Chinese populationSemantic proximity Read ↗

Association between TLR4 (+896A/G and +1196C/T) polymorphisms and gastric cancer risk: an updated meta-analysis.Semantic proximity Read ↗

An updated systematic review of the association between the TLR4 polymorphism rs4986790 and cancers risk.Semantic proximity Read ↗

Toll-like receptor 9 (-1237 T/C, -1486 T/C) and the risk of gastric cancer: a meta-analysis of genetic association studies.Semantic proximity Read ↗

Genetic variants in the regulation region of TLR4 reduce the gastric cancer susceptibility.Semantic proximity Read ↗

Effect of the -2081G/A polymorphism of the TLR4 gene and its interaction with Helicobacter pylori infection on the risk of gastric cancer in Chinese individuals.Semantic proximity Read ↗

Association of polymorphism of TLR4 and CD14 genes with gastroduodenal diseases in Japan.Semantic proximity Read ↗

TLR4 promoter rs1927914 variant contributes to the susceptibility of esophageal squamous cell carcinoma in the Chinese populationSemantic proximity Read ↗

Positive association between Toll-like receptor 4 gene +896A/G polymorphism and susceptibility to gastric carcinogenesis: a meta-analysis.Semantic proximity Read ↗

Associations between the four toll-like receptor polymorphisms and the risk of gastric cancer: a meta-analysis.Semantic proximity Read ↗

The TLR4 gene polymorphisms and susceptibility to cancer: a systematic review and meta-analysis.Semantic proximity Read ↗

A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.