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Article

Positive association between Toll-like receptor 4 gene +896A/G polymorphism and susceptibility to gastric carcinogenesis: a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2013

Zou Tian-Hui, Wang Zhen-Hua, Fang Jing-Yuan

Abstract excerpt

Several studies have investigated the association between the Toll-like receptor 4 (TLR4) gene +896A/G polymorphism and gastric carcinogenesis, including gastric cancer and precancerous gastric lesions. However, published results are inconsistent. So, we performed a meta-analysis to assess whether the TLR4 +896A/G single-nucleotide polymorphism (SNP) is a risk factor in gastric cancer development. We searched...

Topics

Case-Control Studies
Cell Transformation, Neoplastic
Genetic Predisposition to Disease
Genotype
Helicobacter Infections
Helicobacter pylori
Humans
Odds Ratio
Polymorphism, Single Nucleotide
Precancerous Conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk

Stomach Neoplasms

Toll-Like Receptor 4

Source

Identifiers

PMID: 23592020
DOI: 10.1007/s13277-013-0795-y

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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