Article
Heterogeneity of functional properties of Clone 66 murine breast cancer cells expressing various stem cell phenotypes.
PloS one - 1 Jan 2013
Mukhopadhyay Partha, Farrell Tracy, Sharma Gayatri, McGuire Timothy R, O'Kane Barbara, Sharp J Graham
Abstract excerpt
INTRODUCTION: Breast cancer grows, metastasizes and relapses from rare, therapy resistant cells with a stem cell phenotype (cancer stem cells/CSCs). However, there is a lack of studies comparing the functions of CSCs isolated using different phenotypes in order to determine if CSCs are homogeneous or heterogeneous. METHODS: Cells with various stem cell phenotypes were isolated by sorting from Clone 66 murine...
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