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Isolation and Characterization of Potential Cancer Stem Cells from Solid Human Tumors—Potential Applications

1 Dec 2013

Abstract excerpt

Cancer stem cells (CSCs) are a subpopulation of cells within a heterogeneous tumor that have enhanced biologic properties, e.g., increased capacity for self-renewal, increased tumorigenicity, enhanced differentiation capacity, and resistance to chemo- and radiotherapies. This unit describes protocols to isolate and characterize potential cancer stem cells from a solid tumor. These involve creating a single-cell...

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PMID: 24510756
DOI: 10.1002/0471141755.ph1428s63

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