Article
Breast-cancer stem cells-beyond semantics.
The Lancet. Oncology - 1 Jan 2012
Badve Sunil, Nakshatri Harikrishna
Abstract excerpt
Intratumoral heterogeneity in breast cancer is well documented. Although the mechanisms leading to this heterogeneity are not understood, a subpopulation of cancer cells, cancer stem cells (CSCs), that have some phenotypic similarities with adult tissue stem cells, has been suggested to contribute to tumour heterogeneity. It has been postulated that these CSCs are dormant, and by virtue of their low proliferative...
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