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Article

Genetic and epigenetic analysis of putative breast cancer stem cell models

24 Jul 2013

Abstract excerpt

BACKGROUND: Cancer stem cell model hypothesizes existence of a small proportion of tumor cells capable of sustaining tumor formation, self-renewal and differentiation. In breast cancer, these cells were found to be associated with CD44⁺CD24-low and ALDH⁺ phenotype. Our study was performed to evaluate the suitability of current approaches for breast cancer stem cell analyses to evaluate heterogeneity of breast...

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PMID: 23883436
DOI: 10.1186/1471-2407-13-358

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