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Article

Characterizing the HER2/neu status and metastatic potential of breast cancer stem/progenitor cells.

Annals of surgical oncology - 1 Feb 2010

Pommier SuEllen J, Quan Glenda G, Christante Dara, Muller Patrick, Newell Amy E H, Olson Susan B, Diggs Brian, Muldoon Leslie, Neuwelt Edward, Pommier Rodney F

Abstract excerpt

INTRODUCTION: Treatment resistance, long latency, and high recurrence rates suggest that breast cancers arise from defective breast stem cells. HYPOTHESIS: Within cancers, subpopulations of cells will demonstrate differences in stem/progenitor potential, HER2/neu amplification, and gene expression. Related cells will be found in normal breast tissue. METHODS: ER-/PR-/HER2/neu + breast cancer cells were...

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PMID: 19838757
DOI: 10.1245/s10434-009-0730-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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