Article
LDL-c-linked SNPs are associated with LDL-c and myocardial infarction despite lipid-lowering therapy in patients with established vascular disease.
European journal of clinical investigation - 1 Feb 2014
van de Woestijne Anton P, van der Graaf Yolanda, de Bakker Paul I W, Asselbergs Folkert W, de Borst Gert Jan, Algra Ale, Spiering Wilko, Visseren Frank L J
Abstract excerpt
BACKGROUND: Several single-nucleotide polymorphisms (SNPs) are associated with both plasma low-density lipoprotein cholesterol (LDL-c) level and coronary artery disease in the general population. It is unclear whether these associations also apply to patients with vascular disease and whether the associations are independent of lipid-lowering therapy. DESIGN: Single-nucleotide polymorphisms associated with plasma...
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