Article
PUTRA-CV study protocol: a multicentre observational study of ethnic-specific genetic variants and dietary patterns in relation to lipoprotein(a) levels and their association with coronary artery disease severity in Malaysian adults.
BMJ open - 23 Sept 2025
Pannirselvam Sangitha, C Thambiah Subashini, Appannah Geeta, Ling King Hwa, Samsudin Intan Nureslyna, Hooper Amanda J, Yusoff Mohd Rahal, Zakaria Ahmad Firdaus, Razali Rafezah, Kiong Glendon Lau Seng, Zahari Sham Siti Yazmin, Lai Yin Ye, Abdul Rahman Thuhairah Hasrah, Zainal Abidin Imran
Abstract excerpt
INTRODUCTION: Although low-density lipoprotein cholesterol (LDL-C) is established as the primary cardiovascular disease (CVD) risk factor, some individuals with LDL-C within desirable limits still develop coronary artery disease (CAD). Lipoprotein(a) (Lp(a)) has emerged as a genetically determined independent risk factor for CVD. This study aims to investigate Lp(a) by determining its association with coronary...
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