Article
Lipoprotein-associated phospholipase A2 single-nucleotide polymorphisms and cardiovascular events in patients with coronary artery disease.
Journal of cardiovascular medicine (Hagerstown, Md.) - 1 Jan 2015
Maiolino Giuseppe, Lenzini Livia, Pedon Luigi, Cesari Maurizio, Seccia Teresa Maria, Frigo Anna Chiara, Rossitto Giacomo, Caroccia Brasilina, Rossi Gian Paolo
Abstract excerpt
AIMS: We tested the hypothesis that variations in the PLA2G7 gene encoding the lipoprotein-associated phospholipase A2 (Lp-PLA2), an enzyme deemed to have proatherogenic activity, affect the Lp-PLA2 levels and predicts cardiovascular events. METHODS: Using a prospective cohort study design, we investigated incident cardiovascular events as a function of the PLA2G7 gene for rs1805017, rs1805018, and rs1051931...
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