Article
Rs964184 (APOA5-A4-C3-A1) is related to elevated plasma triglyceride levels, but not to an increased risk for vascular events in patients with clinically manifest vascular disease.
PloS one - 1 Jan 2014
van de Woestijne Anton P, van der Graaf Yolanda, de Bakker Paul I W, Asselbergs Folkert W, Spiering Wilko, Visseren Frank L J
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms in the APOA5-A4-C3-A1 gene complex are associated with elevated plasma triglycerides and elevated vascular risk in healthy populations. In patients with clinically manifest vascular disease, hypertriglyceridemia and metabolic syndrome are frequently present, but the contribution of these single nucleotide polymorphisms to plasma triglycerides, effect modification by...
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