Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene variants associated with ischemic stroke: the cardiovascular health study.

Stroke - 1 Feb 2009

Luke May M, O'Meara Ellen S, Rowland Charles M, Shiffman Dov, Bare Lance A, Arellano Andre R, Longstreth W T, Lumley Thomas, Rice Kenneth, Tracy Russell P, Devlin James J, Psaty Bruce M

Abstract excerpt

BACKGROUND AND PURPOSE: The purpose of this study was to determine whether 74 single nucleotide polymorphisms (SNPs), which had been associated with coronary heart disease, are associated with incident ischemic stroke. METHODS: Based on antecedent studies of coronary heart disease, we prespecified the risk allele for each of the 74 SNPs. We used Cox proportional hazards models that adjusted for traditional risk...

Topics

Aged
Alleles
Black People
Brain Ischemia
Cardiovascular Diseases
Coronary Disease
Ethnicity
Female
Gene Frequency
Genetic Variation
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kaplan-Meier Estimate

Male

Polymorphism, Single Nucleotide

Prospective Studies

Risk Factors

Stroke

United States

Source

Open in PubMed Open full text

Identifiers

PMID: 19023099
DOI: 10.1161/STROKEAHA.108.521328
PMCID: PMC2881155

Genes

ABCG2
CALM1
DMXL2
FSTL4
HPS1
ITGAE
KRT4
MYH15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene variants associated with ischemic stroke: the cardiovascular health study.PMID 19023099Read ↗

Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population.Semantic proximity Read ↗

Associations Between Gene Variants of Lipid-Lowering Drug Targets and Adverse Outcomes After Ischemic Stroke.Semantic proximity Read ↗

Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project.Semantic proximity Read ↗

Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.Semantic proximity Read ↗

Stroke Risk Factors, Genetics, and Prevention.Semantic proximity Read ↗

Genetic risk impacts stroke mortality and pathogenesis in patients with ischemic stroke: cohort study of BioBank JapanSemantic proximity Read ↗

Stroke genetics informs drug discovery and risk prediction across ancestriesSemantic proximity Read ↗

The Potential of Single Nucleotide Polymorphisms (SNPs) as Biomarkers and Their Association with the Increased Risk of Coronary Heart Disease: A Systematic Review.Semantic proximity Read ↗

Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans.Semantic proximity Read ↗

WellcomeTrust genome-wide association study of ischemic stroke.Semantic proximity Read ↗

Lipid Metabolism Genes in Stroke Pathogenesis: The AtherosclerosisSemantic proximity Read ↗

Genetic Risk Factors for Ischemic and Hemorrhagic Stroke.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.