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Article

Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease but not with stroke risk in the Heart Protection Study.

Circulation. Cardiovascular genetics - 1 Feb 2011

Hopewell Jemma C, Clarke Robert, Parish Sarah, Armitage Jane, Lathrop Mark, Hager Jorg, Collins Rory

Abstract excerpt

BACKGROUND: Genetic studies have identified 2 single-nucleotide polymorphisms (SNPs) at the LPA locus (rs3798220 and rs10455872) that are strongly and independently related to lipoprotein(a) levels and to coronary disease risk, but their relevance for other atherothrombotic disease is uncertain. METHODS AND RESULTS: These 2 LPA SNPs were examined together as an LPA genotype score for associations with vascular...

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Source

Identifiers

PMID: 21252144
DOI: 10.1161/CIRCGENETICS.110.958371

Genes

LPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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