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Article

Expression of microRNAs is essential for arterial myogenic tone and pressure-induced activation of the PI3-kinase/Akt pathway.

Cardiovascular research - 1 Feb 2014

Bhattachariya Anirban, Dahan Diana, Turczyńska Karolina M, Swärd Karl, Hellstrand Per, Albinsson Sebastian

Abstract excerpt

AIMS: The myogenic response is the intrinsic ability of small arteries to constrict in response to increased intraluminal pressure. Although microRNAs have been shown to play a role in vascular smooth muscle function, their importance in the regulation of the myogenic response is not known. In this study, we investigate the role of microRNAs in the regulation of myogenic tone by using smooth muscle-specific and...

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Share to Arterial Pressure
Share to Calcium Channels, L-Type

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mechanotransduction, Cellular

Share to Phosphatidylinositol 3-Kinase

Share to Renin-Angiotensin System

Share to Ribonuclease III

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Source

Identifiers

PMID: 24233972
DOI: 10.1093/cvr/cvt253

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PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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