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Article

A novel strategy to develop a robust infectious hepatitis C virus cell culture system directly from a clinical isolate.

Journal of virology - 1 Feb 2014

Lu Jie, Xiang Yu, Tao Wanyin, Li Qingchao, Wang Na, Gao Yongfeng, Xiang Xiaogang, Xie Qing, Zhong Jin

Abstract excerpt

Hepatitis C virus (HCV) infection is a leading cause of chronic liver diseases. Progress in the HCV field was greatly enhanced by constructing infectious cDNA clone of JFH-1. Since then, JFH-1-based intra- and intergenotypic recombinants have been developed, and this permitted the study of vaccines and antiviral inhibitors for all genotypes. Recently, highly efficient HCV culture systems have been established by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24227861
DOI: 10.1128/JVI.02929-13
PMCID: PMC3911581

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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