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Article

Production of infectious hepatitis C virus of various genotypes in cell cultures.

Journal of virology - 1 May 2007

Kato Takanobu, Matsumura Takuya, Heller Theo, Saito Satoru, Sapp Ronda K, Murthy Krishna, Wakita Takaji, Liang T Jake

Abstract excerpt

A unique hepatitis C virus (HCV) strain JFH-1 has been shown to replicate efficiently in cell culture with production of infectious HCV. We previously developed a DNA expression system containing HCV cDNA flanked by two self-cleaving ribozymes to generate HCV particles in cell culture. In this study, we produced HCV particles of various genotypes, including 1a (H77), 1b (CG1b), and 2a (J6 and JFH-1), in the...

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Identifiers

PMID: 17301131
DOI: 10.1128/JVI.02334-06
PMCID: PMC1900162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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