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Article

Robust production of infectious viral particles in Huh-7 cells by introducing mutations in hepatitis C virus structural proteins.

The Journal of general virology - 1 Sept 2007

Delgrange David, Pillez André, Castelain Sandrine, Cocquerel Laurence, Rouillé Yves, Dubuisson Jean, Wakita Takaji, Duverlie Gilles, Wychowski Czeslaw

Abstract excerpt

Recently, the characterization of a cell culture system allowing the amplification of an authentic virus, named hepatitis C virus cell culture (HCVcc), has been reported by several groups. To obtain higher HCV particle productions, we investigated the potential effect of some amino acid changes o...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17698659
DOI: 10.1099/vir.0.82872-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17698659-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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