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Article

Viral tropism and antiretroviral drug resistance in HIV-1 subtype C-infected patients failing highly active antiretroviral therapy in Johannesburg, South Africa.

AIDS research and human retroviruses - 1 Mar 2014

Ketseoglou Irene, Lukhwareni Azwidowi, Steegen Kim, Carmona Sergio, Stevens Wendy S, Papathanasopoulos Maria A

Abstract excerpt

Reports show that up to 30% of antiretroviral drug-naive patients in Johannesburg have CXCR4-utilizing HIV-1 subtype C. We assessed whether HIV-1 subtype C-infected individuals failing highly active antiretroviral therapy (HAART) have a higher proportion of CXCR4-utilizing viruses compared to antiretroviral drug-naive patients. The V3 loop was sequenced from plasma from 100 randomly selected HAART-failing...

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Share to Anti-Retroviral Agents
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to HIV Infections

Share to Receptors, HIV

Share to South Africa

Share to Treatment Failure

Share to Viral Tropism

Source

Open in PubMed Open full text

Identifiers

PMID: 24224886
DOI: 10.1089/AID.2013.0267
PMCID: PMC3938925

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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