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Article

Genotypic prediction of tropism of highly diverse HIV-1 strains from Cameroon.

PloS one - 1 Jan 2014

Mbondji-Wonje Christelle, Ragupathy Viswanath, Zhao Jiangqin, Nanfack Aubin, Lee Sherwin, Torimiro Judith, Nyambi Phillipe, Hewlett Indira K

Abstract excerpt

BACKGROUND: The use of CCR5 antagonists involves determination of HIV-1 tropism prior to initiation of treatment. HIV-1 tropism can be assessed either by phenotypic or genotypic methods. Genotypic methods are extensively used for tropism prediction. However, their validation in predicting tropism of viral isolates belonging to group M non-B subtypes remains challenging. In Cameroon, the genetic diversity of HIV-1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to env Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 25379669
DOI: 10.1371/journal.pone.0112434
PMCID: PMC4224497

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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