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Coreceptor tropism determined by genotypic assay in HIV-1 circulating in Thailand, where CRF01_AE predominates.

HIV medicine - 1 May 2014

Phuphuakrat A, Phawattanakul S, Pasomsub E, Kiertiburanakul S, Chantratita W, Sungkanuparph S

Abstract excerpt

OBJECTIVES: Chemokine (C-C motif) receptor 5 (CCR5) inhibitors are a novel class of antiretroviral agents that are promising for treatment of patients who harbour the HIV-1 R5 strain. Data on coreceptor tropism in non-B HIV-1 subtypes are limited. We studied coreceptor tropism in HIV-1 circulating in Thailand, where CRF01_AE predominates, using a genotypic assay. METHODS: We compiled V3 sequences of HIV-1 strains...

Topics

Adult
Cross-Sectional Studies
Female
Genotype
HIV Infections
HIV-1
Humans
Logistic Models
Male
Middle Aged
Phenotype
Receptors, CCR5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thailand

Viral Load

Viral Tropism

Source

Identifiers

PMID: 24215399
DOI: 10.1111/hiv.12108

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Coreceptor tropism determined by genotypic assay in HIV-1 circulating in Thailand, where CRF01_AE predominates.PMID 24215399Read ↗

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