Monophylogenetic HIV-1C epidemic in Ethiopia is dominated by CCR5-tropic viruses-an analysis of a prospective country-wide cohort.

doi:10.1186/s12879-016-2163-1

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Article

Monophylogenetic HIV-1C epidemic in Ethiopia is dominated by CCR5-tropic viruses-an analysis of a prospective country-wide cohort.

BMC infectious diseases - 6 Jan 2017

Kalu Amare Worku, Telele Nigus Fikrie, Gebreselasie Solomon, Fekade Daniel, Abdurahman Samir, Marrone Gaetano, Sönnerborg Anders

Abstract excerpt

BACKGROUND: CCR5 coreceptor using HIV-1 subtype C (HIV-1C) has been reported to dominate the Ethiopian epidemic. However, almost all data have been obtained from two large cities in the central and north-west regions and recent data is lacking. METHODS: Plasma were obtained from 420 treatment-naïve patients recruited 2009-2011 to a large country-wide Ethiopian cohort. The V3 region was sequenced and the...

Topics

Adult
CD4-Positive T-Lymphocytes
Cohort Studies
Epidemics
Ethiopia
Female
Genotype
HIV Infections
HIV-1
Host-Pathogen Interactions
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Prospective Studies

Receptors, CCR5

Treatment Outcome

Viral Load

Viral Tropism

Source

Open in PubMed Open full text

Identifiers

PMID: 28061826
DOI: 10.1186/s12879-016-2163-1
PMCID: PMC5219668

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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