Article
Relationship between the COMT-Val158Met and BDNF-Val66Met polymorphisms, childhood trauma and psychotic experiences in an adolescent general population sample.
PloS one - 1 Jan 2013
Ramsay Hugh, Kelleher Ian, Flannery Padraig, Clarke Mary C, Lynch Fionnuala, Harley Michelle, Connor Dearbhla, Fitzpatrick Carol, Morris Derek W, Cannon Mary
Abstract excerpt
OBJECTIVE: Psychotic experiences occur at a much greater prevalence in the population than psychotic disorders. There has been little research to date, however, on genetic risk for this extended psychosis phenotype. We examined whether COMT or BDNF genotypes were associated with psychotic experiences or interacted with childhood trauma in predicting psychotic experiences. METHOD: Psychiatric interviews and...
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