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Article

Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes.

Acta psychiatrica Scandinavica - 1 Jan 2014

Alemany S, Arias B, Fatjó-Vilas M, Villa H, Moya J, Ibáñez M I, Ortet G, Gastó C, Fañanás L

Abstract excerpt

OBJECTIVE: To test whether the association between childhood abuse, cannabis use and psychotic experiences (PEs) was moderated by the COMT (catechol-O-methyltransferase) gene. METHOD: Psychotic experiences (PEs), childhood abuse, cannabis use and COMT Val158Met genotypes were assessed in 533 individuals from the general population. Data were analysed hierarchically by means of multiple linear regression models....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23445265
DOI: 10.1111/acps.12108

Genes

COMT

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