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Article

Childhood trauma interacted with BDNF Val66Met influence schizophrenic symptoms.

Medicine - 1 Mar 2018

Bi Xiao-Jiao, Lv Xiao-Min, Ai Xian-Ying, Sun Meng-Meng, Cui Kai-Yan, Yang Li-Min, Wang Li-Na, Yin Ai-Hua, Liu Lan-Fen

Abstract excerpt

The gene - environment (G × E) interaction effect is involved in severe mental disorders. However, whether the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism participates in the childhood-abuse influenced schizophrenic symptoms remains unclear. We examined the interaction between BDNF Val66Met, and childhood trauma (ChT) on psychotic symptoms in a Chinese Han population.To estimate the G × E...

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Identifiers

PMID: 29595641
DOI: 10.1097/MD.0000000000010160
PMCID: PMC5895403

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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