Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between COMT Val158 Met polymorphism and childhood trauma predicts risk for depression in men.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Aug 2022

Xavier Janaína, Bastos Clarissa Ribeiro, Camerini Laísa, Amaral Paola Bajadares, Jansen Karen, de Mattos Souza Luciano Dias, da Silva Ricardo Azevedo, Pinheiro Ricardo Tavares, Lara Diogo Rizzato, Ghisleni Gabriele

Abstract excerpt

Depression is a disabling illness with complex etiology. While the catechol-O-methyltransferase (COMT) gene, in particular the functional Val158 Met polymorphism, has been related to depression, the mechanisms underlying this gene-disease association are not completely understood. Therefore, we explore the association of COMT Val158 Met polymorphism with depression as well as its interaction with childhood trauma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adverse Childhood Experiences
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Identifiers

PMID: 35441426
DOI: 10.1002/jdn.10186

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between COMT Val158 Met polymorphism and childhood trauma predicts risk for depression in men.PMID 35441426Read ↗

COMT Val158Met polymorphism protects the impact of a mother's history of childhood trauma on emotional and behavioural problems in preschool children.Semantic proximity Read ↗

Association between genes, stressful childhood events and processing bias in depression vulnerable individuals.Semantic proximity Read ↗

Genetic pathways to posttraumatic stress disorder and depression in children: Investigation of catechol-O-methyltransferase (COMT) Val158Met using different PTSD diagnostic models.Semantic proximity Read ↗

Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium.Semantic proximity Read ↗

The interaction of early life experiences with COMT val158met affects anxiety sensitivity.Semantic proximity Read ↗

The association between trauma exposure, polygenic risk and individual depression symptoms.Semantic proximity Read ↗

Relationship between the COMT-Val158Met and BDNF-Val66Met polymorphisms, childhood trauma and psychotic experiences in an adolescent general population sample.Semantic proximity Read ↗

Genome-by-Trauma Exposure Interactions in Adults With Depression in the UK Biobank.Semantic proximity Read ↗

Interplay between COMT Val158Met, childhood adversities and sex in predicting panic pathology: Findings from a general population sample.Semantic proximity Read ↗

The relationship between childhood abuse and dissociation. Is it influenced by catechol-O-methyltransferase (COMT) activity?Semantic proximity Read ↗

Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank.Semantic proximity Read ↗

Effect of polygenic risk scores on depression in childhood trauma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.