Childhood trauma, BDNF Val66Met and subclinical psychotic experiences. Attempt at replication in two independent samples.

doi:10.1016/j.jpsychires.2016.08.014

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Article

Childhood trauma, BDNF Val66Met and subclinical psychotic experiences. Attempt at replication in two independent samples.

Journal of psychiatric research - 1 Dec 2016

de Castro-Catala Marta, van Nierop Martine, Barrantes-Vidal Neus, Cristóbal-Narváez Paula, Sheinbaum Tamara, Kwapil Thomas R, Peña Elionora, Jacobs Nele, Derom Catherine, Thiery Evert, van Os Jim, van Winkel Ruud, Rosa Araceli

Abstract excerpt

Childhood trauma exposure is a robust environmental risk factor for psychosis. However, not all exposed individuals develop psychotic symptoms later in life. The Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) has been suggested to moderate the psychosis-inducing effects of childhood trauma in clinical and nonclinical samples. Our study aimed to explore the interaction effect between...

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PMID: 27596955
DOI: 10.1016/j.jpsychires.2016.08.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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