Article
Mrc1 and Srs2 are major actors in the regulation of spontaneous crossover.
The EMBO journal - 21 Jun 2006
Robert Thomas, Dervins Delphine, Fabre Francis, Gangloff Serge
Abstract excerpt
In vegetative cells, most recombination intermediates are metabolized without an association with a crossover (CO). The avoidance of COs allows for repair and prevents genomic rearrangements, potentially deleterious if the sequences involved are at ectopic locations. We have designed a system that permits to screen spontaneous intragenic recombination events in Saccharomyces cerevisiae and to investigate the CO...
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