Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution, functional divergence and conserved exon-intron structure of bHLH/PAS gene family.

Molecular genetics and genomics : MGG - 1 Feb 2014

Yan Jun, Ma Zhaowu, Xu Xiaopeng, Guo An-Yuan

Abstract excerpt

bHLH/PAS genes encode a family of basic helix-loop-helix (bHLH) transcription factors with bHLH, PAS and PAS_3 domain. bHLH/PAS genes are involved in many essential physiological and developmental processes, such as hypoxic response neural development, the circadian clock, and learning ability. Despite their important functions, the origin and evolution of this bHLH/PAS gene family has yet to be elucidated. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basic Helix-Loop-Helix Transcription Factors
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Introns

Share to Multigene Family

Share to Selection, Genetic

Share to Sequence Homology, Amino Acid

Share to Vertebrates

Source

Identifiers

PMID: 24202550
DOI: 10.1007/s00438-013-0786-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution, functional divergence and conserved exon-intron structure of bHLH/PAS gene family.PMID 24202550Read ↗

Hypoxia Inducible Factor (HIF) transcription factor family expansion, diversification, divergence and selection in eukaryotes.Semantic proximity Read ↗

Diversification and molecular evolution of ATOH8, a gene encoding a bHLH transcription factor.Semantic proximity Read ↗

A natural classification of the basic helix-loop-helix class of transcription factors.Semantic proximity Read ↗

The Basic Helix-Loop-Helix-PAS Protein MOP9 Is a Brain-Specific Heterodimeric Partner of Circadian and Hypoxia FactorsSemantic proximity Read ↗

Molecular evolution of the metazoan PHD-HIF oxygen-sensing system.Semantic proximity Read ↗

Research progresses on non-coding DNA regulatory elements in the evolution of animal adaptive traits.Semantic proximity Read ↗

A non-synonymous SNP with the allele frequency correlated with the altitude may contribute to the hypoxia adaptation of Tibetan chicken.Semantic proximity Read ↗

Core and Flanking bHLH-PAS:DNA interactions mediate specificity and drive obesitySemantic proximity Read ↗

Cooption of polyalanine tract into a repressor domain in the mammalian transcription factor HoxA11Semantic proximity Read ↗

Genome-wide analysis of the FIGLA gene in MammalsSemantic proximity Read ↗

Nach is a novel ancestral subfamily ofthe CNC-bZIP transcription factors selected during evolution from the marine bacteria to humanSemantic proximity Read ↗

The Participation of the Intrinsically Disordered Regions of the bHLH-PAS Transcription Factors in Disease DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.