Article
A non-synonymous SNP with the allele frequency correlated with the altitude may contribute to the hypoxia adaptation of Tibetan chicken.
PloS one - 1 Jan 2017
Li Sichen, Li Diyan, Zhao Xiaoling, Wang Yan, Yin Huadong, Zhou Lanyun, Zhong Chengling, Zhu Qing
Abstract excerpt
The hypoxia adaptation to high altitudes is of considerable interest in the biological sciences. As a breed with adaptability to highland environments, the Tibetan chicken (Gallus gallus domestics), provides a biological model to search for genetic differences between high and lowland chickens. To address mechanisms of hypoxia adaptability at high altitudes for the Tibetan chicken, we focused on the Endothelial...
Topics
- Adaptation, Physiological
- Alleles
- Altitude
- Altitude Sickness
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- Breeding
- Chickens
- Conserved Sequence
- Gene Frequency
- Genetic Association Studies