Article
Short (GT)n microsatellite repeats in the heme oxygenase-1 gene promoter are associated with antioxidant and anti-inflammatory status in Mexican pediatric patients with sepsis.
The Tohoku journal of experimental medicine - 1 Nov 2013
Vázquez-Armenta Gabriela, González-Leal Natalia, J Vázquez-de la Torre Mayra, Muñoz-Valle José Francisco, Ramos-Márquez Martha E, Hernández-Cañaveral Iván, Plascencia-Hernández Arturo, Siller-López Fernando
Abstract excerpt
An adequate immune and antioxidant response is a key to the resolution of sepsis. Heme oxygenase-1 (HMOX1) is a stress protein with a polymorphic (GT)n repeat in its gene promoter that regulates its expression in response to oxidative injury, such as that present in sepsis. HMOX1 is the rate-limi...
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