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Article

HMOX1 promoter (GT)n polymorphim is associated with childhood-onset systemic lupus erythematosus but not with juvenile rheumatoid arthritis in a Mexican population.

Clinical and experimental rheumatology - 1 Jan 2000

Córdova Emilio J, Martínez-Hernández Angélica, Ramírez-Bello Julian, Velázquez-Cruz Rafael, Centeno Federico, Baca Vicente, Orozco Lorena

Abstract excerpt

OBJECTIVES: The heme oxigenase 1 (HO-1), a rate-limiting enzyme for heme degradation, is an important cytoprotective protein. Transcriptional activity of HO-1 coding gene (HMOX1) can be regulated by the presence of a dinucleotide repeat polymorphism (GT)n at its promoter region. Accordingly, length of (GT)n repeat has been associated with susceptibility to several diseases. We investigated whether the HMOX1 (GT)n...

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Source

Identifiers

PMID: 22338608

Genes

HMOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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HMOX1 promoter (GT)n polymorphim is associated with childhood-onset systemic lupus erythematosus but not with juvenile rheumatoid arthritis in a Mexican population.PMID 22338608Read ↗

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