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Article

HMOX1 genetic polymorphisms and outcomes in infectious disease: A systematic review.

PloS one - 1 Jan 2022

Hamilton Fergus W, Somers Julia, Mitchell Ruth E, Ghazal Peter, Timpson Nicholas J

Abstract excerpt

INTRODUCTION: Heme-oxygenase 1 (HMOX1) is a critical stress response gene that catalyzes the multistep oxidation of heme. A GT(n) repeat of variable length in the promoter in has been associated with a wide range of human diseases, including infections. This paper aims to summarise and systematically review associations between the length of the HMOX1 GT(n) promoter and infectious disease in humans. METHODS: A...

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Identifiers

PMID: 35551540
DOI: 10.1371/journal.pone.0267399
PMCID: PMC9098073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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