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Article

Role of heme oxygenase-1 in human endothelial cells: lesson from the promoter allelic variants.

Arteriosclerosis, thrombosis, and vascular biology - 1 Aug 2010

Taha Hevidar, Skrzypek Klaudia, Guevara Ibeth, Nigisch Anneliese, Mustafa Stefan, Grochot-Przeczek Anna, Ferdek Pawel, Was Halina, Kotlinowski Jerzy, Kozakowska Magdalena, Balcerczyk Aneta, Muchova Lucie, Vitek Libor, Weigel Guenter, Dulak Jozef, Jozkowicz Alicja

Abstract excerpt

OBJECTIVE: Heme oxygenase-1 (HO-1) is an antioxidative, antiinflammatory, and cytoprotective enzyme that is induced in response to cellular stress. The HO-1 promoter contains a (GT)n microsatellite DNA, and the number of GT repeats can influence the occurrence of cardiovascular diseases. We eluci...

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Identifiers

PMID: 20508205
DOI: 10.1161/ATVBAHA.110.207316
PMCID: PMC2906705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20508205-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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