Associations between Single Nucleotide Polymorphisms of High Mobility Group Box 1 Protein and Clinical Outcomes in Korean Sepsis Patients.

doi:10.3349/ymj.2016.57.1.111

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Article

Associations between Single Nucleotide Polymorphisms of High Mobility Group Box 1 Protein and Clinical Outcomes in Korean Sepsis Patients.

Yonsei medical journal - 1 Jan 2016

Lee Kwangha, Chang Youjin, Song Kyuyoung, Park Yun Young, Huh Jin Won, Hong Sang Bum, Lim Chae Man, Koh Younsuck

Abstract excerpt

PURPOSE: High mobility group box 1 (HMGB1) plays a central role in the pathogenesis of sepsis and multiple organ dysfunction syndromes. We investigated the associations of a single nucleotide polymorphism (SNP; rs1045411) in HMGB1 with various clinical parameters, severity, and prognosis in patients with sepsis, severe sepsis, or septic shock. MATERIALS AND METHODS: We enrolled 212 adult patients followed for 28...

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PMID: 26632390
DOI: 10.3349/ymj.2016.57.1.111
PMCID: PMC4696941

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HMGB1

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