Article
Accuracy of somatic variant detection in multiregional tumor sequencing data
2019-05-31
Abstract excerpt
Multiregional bulk sequencing data is necessary to characterize intratumor genetic heterogeneity. Novel somatic variant calling approaches aim to address the particular characteristics of multiregional data, but it remains unclear to which extent they improve compared to single-sample strategies. Here we compared the performance of 16 single-nucleotide variant calling approaches on multiregional sequencing data un...
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Identifiers and source
- Literature Corpus work
- 7a205c04-f9ad-552f-bb3b-dc78870791cd
- DOI
- 10.1101/655605