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Article

Dicer expression is essential for adult midbrain dopaminergic neuron maintenance and survival.

Molecular and cellular neurosciences - 1 Jan 2014

Pang Xueyan, Hogan Eric M, Casserly Alison, Gao Guangping, Gardner Paul D, Tapper Andrew R

Abstract excerpt

The type III RNAse, Dicer, is responsible for the processing of microRNA (miRNA) precursors into functional miRNA molecules, non-coding RNAs that bind to and target messenger RNAs for repression. Dicer expression is essential for mouse midbrain development and dopaminergic (DAergic) neuron maintenance and survival during the early post-natal period. However, the role of Dicer in adult mouse DAergic neuron...

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Identifiers

PMID: 24184162
DOI: 10.1016/j.mcn.2013.10.009
PMCID: PMC3944994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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