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Article

The control of dopamine neuron development, function and survival: insights from transgenic mice and the relevance to human disease.

Current medicinal chemistry - 1 May 2003

Eells J B

Abstract excerpt

Transgenic technology, especially the use of homologous recombination to disrupt specific genes to produce knockout mice, has added considerably to the understanding of dopamine (DA) neuron develop, survival and function. The current review summarizes results from knockout mice with the target disruption of genes involved in the development of DA neurons (engrailed 1 and 2, lmx1b, and Nurr1), in maintaining DA...

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Identifiers

PMID: 12678688
DOI: 10.2174/0929867033457700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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