Article
Dicer is essential for neuronal polarity.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Nov 2012
Li Zhi, He Xi, Feng Jiexiong
Abstract excerpt
Dicer, an RNase III endonuclease, is the enzyme which cleaves microRNA (miRNA) and small interfering RNA (siRNA) precursors into 21-25 nucleotide species. This cleavage is an essential step in the biogenesis of these small noncoding RNA molecules. In their mature forms, siRNA and miRNAs function to regulate gene expression through different mechanisms (Bartel, 2004). To investigate the role of Dicer and microRNAs...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
