Article
Dicer and microRNAs protect adult dopamine neurons.
Cell death & disease - 25 May 2017
Chmielarz Piotr, Konovalova Julia, Najam Syeda Sadia, Alter Heike, Piepponen Timo Petteri, Erfle Holger, Sonntag Kai C, Schütz Günther, Vinnikov Ilya A, Domanskyi Andrii
Abstract excerpt
MicroRNAs (miRs) are important post-transcriptional regulators of gene expression implicated in neuronal development, differentiation, aging and neurodegenerative diseases, including Parkinson's disease (PD). Several miRs have been linked to PD-associated genes, apoptosis and stress response pathways, suggesting that deregulation of miRs may contribute to the development of the neurodegenerative phenotype. Here,...
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