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Article

Short interfering RNAs (siRNAs) for reducing dopaminergic phenotypic markers.

Journal of neuroscience methods - 30 Dec 2003

Bäckman Cristina, Zhang YaJun, Hoffer Barry J, Tomac Andreas C

Abstract excerpt

Short interfering RNAs (siRNAs) are double-stranded RNAs of approximately 19-29 nucleotides designed to suppress the expression of homologous genes by a process known as RNA interference (RNAi). In this study we have characterized several short interfering RNAs to reduce (knockdown) the expression of genes related to the dopaminergic system of the ventral mesencephalon. We report here effective suppression of all...

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PMID: 14659823
DOI: 10.1016/s0165-0270(03)00236-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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